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Claude Opus 4.6 vs Hermes 3 405B Instruct

Side-by-side API pricing and Artificial Analysis performance for Claude Opus 4.6 (Anthropic) and Hermes 3 405B Instruct (Nous Research). Green cells mark the better value in each row.

Prices updated Jul 22, 2026, 3:55 AM UTC · refreshed hourly

Claude Opus 4.6

Anthropic

Hermes 3 405B Instruct

Nous Research

Pricing
Input $/1M$5.00$1.00
Output $/1M$25.00$1.00
Blended $/1M (3:1)$10.00$1.00
RAG example (30K in / 2K out)$0.2$0.032
Quality & speed
Intelligence Index37.8
Coding Index
Agentic Index
Output speed (tok/s)57
Time to first token1.85s
Specs
Context window1M131K
Input modalitiestext, image, filetext

FAQ

Which is cheaper, Claude Opus 4.6 or Hermes 3 405B Instruct?

Hermes 3 405B Instruct has the lower blended API price at $1.00 per 1M tokens (3:1 input:output mix), versus $10.00 for the other model. Prices are live from OpenRouter and refresh about hourly.

Which is better for RAG workloads?

For a typical RAG request (30K input / 2K output tokens), Hermes 3 405B Instruct costs about $0.032 per request versus $0.2. Also compare context windows: Claude Opus 4.6 offers 1M and Hermes 3 405B Instruct offers 131K.

Which scores higher on Artificial Analysis benchmarks?

Claude Opus 4.6 leads on the Artificial Analysis Intelligence Index (37.8 vs —). Check coding and agentic indices on this page for workload-specific tradeoffs.